Spondylo-epiphysial dysplasia tarda with progressive arthropathy. A "new" disorder of autosomal recessive inheritance

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Spondylo-epiphysial dysplasia tarda with progressive arthropathy. A "new" disorder of autosomal recessive inheritance.

Fifteen patients with an inherited skeletal dysplasia which is considerably more crippling than the usual form of spondylo-epiphysial dysplasia tarda are presented. The disorder has a striking clinical, though not radiological, resemblance to rheumatoid arthritis but with the addition of platyspondyly. It has not previously been described, although it is possible that the case referred to by Ma...

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Spondyloepiphyseal dysplasia tarda with progressive arthropathy (SEDT-PA) is a rare autosomal recessive skeletal dysplasia affecting primarily the articular cartilage. Here we present a nine-year-old girl from Middle Anatolia (Sivas) with SEDT-PA. Her complaints were pain and progressive deformity of the joints. She had a short stature with increased thoracic kyphosis and lumbar lordosis. The r...

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Spondyloepiphyseal dysplasia tarda: a new autosomal recessive variant with mental retardation.

A new variant of spondyloepiphyseal dysplasia tarda with mild to moderate mental retardation is described in three daughters born to healthy, consanguineous parents. The mode of inheritance is compatible with that of an autosomal recessive disorder. The identification of this variant is important, as it enables more precise counselling in families in which sporadic cases with this form of prese...

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ژورنال

عنوان ژورنال: The Journal of Bone and Joint Surgery. British volume

سال: 1982

ISSN: 0301-620X,2044-5377

DOI: 10.1302/0301-620x.64b4.6807993